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Protecting Tissues: Some animal studies have shown that GLP-1 receptor agonists may protect tissues from inflammation-related damage
This includes prioritizing drugs with proven outcome benefits in those at high risk, even as metformin remains appropriate for many others
Common side effects may include nausea, diarrhoea, decreased appetite, vomiting, constipation, indigestion, and stomach pain
Essential baseline investigations typically include: Lipid profile : Total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides to establish baseline values HbA1c or fasting glucose : To screen for diabetes or prediabetes Liver function tests : As baseline measurement, particularly if considering long-term treatment Thyroid function tests : To exclude thyroid disorders that may affect weight Blood pressure measurement : To assess overall cardiovascular risk Renal function : Particularly important for patients on multiple medications Pregnancy test : Where appropriate, before starting treatment Cardiovascular risk assessment using tools such as QRISK3 helps determine the overall 10-year risk of cardiovascular disease
No todos los estudios parten del mismo punto y, en general, los resultados son ms consistentes cuando existe un contexto concreto (por ejemplo, riesgo de alteracin de los niveles de carnitina)
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